Targeted Protein Degradation: Methods and Protocols

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Biology and other natural sciences - Molecular
Targeted Protein Degradation: Methods...

Targeted Protein Degradation: Methods and Protocols

Name: Targeted Protein Degradation: Methods and Protocols
ISBN: 9781071616642

Angela M. Cacace, Christopher M. Hickey, Miklós Békés

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This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.

カテゴリー:

Biology and other natural sciences - Molecular

巻:

2365

年:

2021

版:

出版社:

Humana

言語:

english

ページ: